Optimized Preparation Method of Dess-Martin Oxidant
HU Chen-Fei2, TANG Xiao1, LI Ping2, MIAO Zhi-Wei1
1. Research Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China; 2. School of Chemistry and Chemical Engineering, Tianjin University of Technology, Tianjin 300384, China
Abstract Dess-Martin oxidant is an important reagent for oxidizing hydroxyl compounds to aldehydes and ketones in organic synthesis, which is routinely prepared under anhydrous and anoxybiotic conditions. Here we demonstrate the optimized preparation method with 2-iodobenzoic acid as the starting material for the synthesis of Dess-Martin oxidant under laboratory conditions.
