Abstract This paper was about the thinking of the abandoned hazardous chemicals in high school chemistry laboratory which was evoked by the Tianjin hazardous chemicals big bang, and deeply analyzed the reasons, features and status quo of high school chemistry laboratory abandoned hazardous chemicals produced, which should arouse the attention of the relevant departments. Combining with the actual situation of high school, this paper put forward some effective suggestions respectively from the training system, management system, database, recycling mechanism, partner relationship, and tender condition and so on.