Abstract The chemistry experiment class was carried out in the way of micro inquiry learning, and the concrete implementation steps included background knowledge investigation, experiment scheme design, experiment inquiry, experiment defense and exchange. The implementation process emphasized the implementation of learning objectives and diversification of evaluation methods. After a semester of implementation, classroom micro inquiry learning had made a great influence on teachers and students. The results of the questionnaire survey indicated that teachers' new teaching concepts had been better implemented and their teaching ability had been improved; students' ability to spot problems, ask questions, and solve problems had been enhanced, the initiative of knowledge acquisition had been enhanced, and the ability of group cooperation had been enhanced.