Abstract A comprehensive experiment was designed to apply the manufacturing of nanozyme paper chip biochemical sensors, modern analysis and testing technology, and sensing detection to the teaching experiments of materials science and engineering majors, in order to improve students' comprehensive practical abilities. The experiment consists of three main parts: research on the manufacturing process of nanozyme paper chip biochemical sensors, performance analysis of paper chips, and research on ascorbic acid detection methods. Nanozyme paper chips were manufactured using wax spray printing method, and their structure and properties were analyzed using scanning electron microscopy, X-ray diffractometer, thermogravimetric analyzer and ImageJ. A colorimetric method was used to establish a detection method for ascorbic acid. By conducting this experiment, students can understand the cutting-edge knowledge of materials science, master the basic principles and testing steps of relevant modern analysis and testing techniques, and proficiently master professional experimental operations and data processing methods, thereby improving their comprehensive practical ability and professional quality.
SU Yi-Qian, ZHANG LI-Yuan, CHEN Ying, LIN Peng-Cheng. Comprehensive Experimental Design of Materials Science and Engineering: Fabrication and Ascorbic Acid Detection of Biosensors Based on Nanozyme[J]. Chinese Journal of Chemical Education, 2025, 46(8): 52-58.