Abstract This paper introduces the reaction principle of OsO4catalyzing dihydroxylation of asym alkene,and the catalytic cycle of dihydroxylation of alkene when N-methylmorpholine-N-oxide(NMO)and K3[Fe(CN)6] as oxidant.In addition,this paper introduces the mechanism of stereoselectivity of this cata-lytic reaction and its investigation development,and the selection of chiral ligand in catalytic system.
