Abstract The exploration of multidimensional interactive teaching mode of polymer chemistry were carried out from the characteristics of polymer chemistry course and teaching situation at present, and also considering for the features and specialized training objectives of the major of applied chemistry. The exploration developed from two levels both within and outside of the classroom, focusing on the combination of theory and practice. It was designed to help students develop interest in learning and constantly inspire the passion of students to learn polymer chemistry. And through multi-dimensional interactive teaching mode, we tried to provide students with more space for self-exploration and reflection,enhance the initiative of students to study,gradually improve the professional literacy and ability of students, and effectively improve teaching quality.