Abstract Yu He-qin, applied himself to the practice of sinicization of science, was a new-typed scholar in the late Qing Dynasty and Republic of China. This paper discussed Yu He-qin's papers such as Chemical Nomenclature, The list of Chinese Chemistry Terms, etc., analysed his introduction and sinicization of “Hua” nomenclature for inorganic compounds, and presented the academic influence of his“Hua” nomenclature.