Abstract Based on requirements of cultivating applied talents, a novel teaching mode in organic chemistry course was constructed through the application of sandwich teaching method and the modular construction of the teaching contents. As a result, the systematic nature of knowledge dissemination and the students' application ability were enhanced. Under the guidance of sandwich teaching mode, the corresponding teaching methods and examination methods were reformed resulting in the enhancement of the proportion of practical links and the students' participation. Besides, student-centered and teacher-oriented teaching mode was highlighted. According to the investigation and analysis, the enthusiasm of students is high. The ability of analyzing and solving problems, effective teamwork skills are improved greatly. Therefore, the sandwich teaching mode in organic chemistry course is suitable for the cultivation of applied talents.
