Abstract 1,4-Dimethoxypillar[5]arene (DMP[5]) was synthesized and the inclusion interactions with 1,6-diaminohexane were studied by NMR titration. The results showed that DMP[5]and 1,6-diaminohexane form a 1:1 complex with an association constant of 49 L/mol, which was calculated by DynaFit. As an organic chemistry experiment for undergraduate students, it may help students learn the leading edge of supramolecular chemistry, stimulate interests and improve the comprehensive ability.
LIU Shuo, WANG Xiao-Jing, HAN Jie. Synthesis of 1, 4-Dimethoxypillar[5]arene and Determination of Association Constant for 1, 4-Dimethoxypillar[5]arene and 1, 6-Diaminohexane[J]. Chinese Journal of Chemical Education, 2017, 38(6): 22-25.