Abstract Herein we reported the synthesis of 6-amino hexanoic acid starting from cyclohexanone via three steps including oximation, Beckmann rearrangement, and hydrolysis. After purification, the structure of 6-amino-hexanoic acid was confirmed by 1H NMR and 13C NMR. The experiment, combining tightly with organic synthesis curriculum, covers a lot of experimental operation and is suitable for comprehensive chemistry experiment for students.
LIANG Jing, TANG Shi-Biao, ZHU Xue-Jiao, WANG Xin. Synthesis and Characterization of 6-Amino Hexanoic Acid[J]. Chinese Journal of Chemical Education, 2018, 39(24): 40-43.
