Direct Resolution of Enantiomers of D,L-Alanine by Paper Chromatography with Vancomycin as Impregnating Agent
CUI Ruo-Yu1, LI Mei-Na1, FANG Ting1, YUAN Chen2, YAN Dong-Peng3
1. Affiliated Middle School of Shanghai Normal University, Shanghai 201112, China;
2. School of Chemistry and Chemical Engineering, Shanghai Jiaotong University, Shanghai 200240, China;
3. Department of Chemistry, Beijing Normal University, Beijing 100875, China
Abstract In this work, we confirm that direct resolution of enantiomers for D,L-alanine can be achieved on paper using vancomycin as chiral impregnating reagent. The effects of the ratio of mobile phase, concentration of chiral selector had been studied in details. Thus, the technique reported here is flexible, simple, direct and economical, and may become the facile method compared with other chromatographic techniques towards fast routine analysis. It is therefore suitable for experimental teaching and industrial applications.
CUI Ruo-Yu, LI Mei-Na, FANG Ting, YUAN Chen, YAN Dong-Peng. Direct Resolution of Enantiomers of D,L-Alanine by Paper Chromatography with Vancomycin as Impregnating Agent[J]. Chinese Journal of Chemical Education, 2018, 39(4): 22-24.
