Abstract A research-oriented comprehensive chemistry experiment of preparation of 2-o-chlorobenzamido naphtho[1,2-d]thiazole by manganese acetate(Ⅲ) is introduced. The self-prepared manganese acetate(Ⅲ) as catalyst is applied for catalyzing 1-naphthyl-3-o-chlorobenoylthiourea to synthesize 2-o-chlorobenzamido naphtho[1,2-d]thiazole. Through this experiment teaching, students can master the synthesis methods of the manganese acetate(Ⅲ), 1-naphthyl-3-o-chlorobenoylthiourea and 2-o-chlorobenzamido naphtho[1,2-d]thiazole, and can grasp general methods of organic compounds' structure characterization. It is more important that the experiment teaching can cultivate students' practical ability, research and creative ability, and students' comprehensive ability to use knowledge. This experiment gathers inorganic synthesis experiment, organic synthesis experiment and instrumental analysis experiment, and has good operability and practicability. It can be established as a research-oriented comprehensive chemical experiment or open experiment.
LIU Tian-Bao, PENG Yan-Fen. A Research-Oriented Comprehensive Chemistry Experiment of Preparation of Naphthothiazole Derivatives by Manganese Acetate[J]. Chinese Journal of Chemical Education, 2018, 39(4): 31-34.