Abstract This article introduces the blended teaching design of fluoride in inorganic chemistry courses based on Moso Teach. This teaching design combines mobile phone with teaching reasonably, making mobile phone a powerful learning tool for students. In the process of teaching, some questions are designed in the classroom according to the teaching content,and every student participates in funny and active learning process by use of the functions of "brainstorming", "answer discussion" or "group task" in Moso Teach. Teacher can understand the changes in students' cognition and interests by use of the function of "Vote/Questionnaire" in Moso Teach, and improve the teaching methods on this basis. According to the survey, the classroom teaching can be promoted by the Moso Teach and this teaching design was accepted by most of students.