Comprehensive Experiment in Organic Chemistry: Synthesis, Characterization and Properties of BINOL-Based Chiral Compound with Aggregation-Induced Emission Characteristics
ZHAO Na**, LI Nan
School of Chemistry & Chemical Engineering, Shaanxi Normal University, Xi'an 710119, China
Abstract In this paper, the cutting edge result was introduced into the comprehensive experiment in organic chemistry. We designed a comprehensive experiment on the synthesis, characterization and properties of BINOL-based chiral compound with aggregation-induced emission characteristics. Based on this experiment, the students will learn several basic organic transformations, such as protection of phenol hydroxyl groups, formylation and condensation reactions. Meanwhile, they will characterize the chemical structure of this chiral compound by using nuclear magnetic resonance and mass spectroscopies, and investigate its optical properties by employing UV-Vis, emission and circular dichroism spectroscopies. This experiment will help students to have a better understanding about the phenomenon and mechanism of aggregation-induced emission. This experiment combined various organic reactions and characterization methods, which is conducive to systematically improving the experimental ability, scientific research ability and inspiring the interests in scientific research of students.
ZHAO Na, LI Nan. Comprehensive Experiment in Organic Chemistry: Synthesis, Characterization and Properties of BINOL-Based Chiral Compound with Aggregation-Induced Emission Characteristics[J]. Chinese Journal of Chemical Education, 2021, 42(16): 60-65.