Abstract Combined with scientific research achievements and experimental teaching experience,the traditional experiment of methylation reaction in organic chemistry experiment was improved. The traditional methylation reagents involved in the teaching materials have disadvantage such as high toxicity,which is not conducive to the implementation of experimental teaching. Therefore,this paper proposes to replace traditional methylation reagents with methyl trifluoroacetate from scientific research achievements and applies it to the experimental teaching of organic chemistry for undergraduates,so as to enhance students’ understanding of the theoretical knowledge of methylation reaction. This experiment combines novel scientific research content and introduces the design idea of scientific research experiment,which is not only conducive to students to better grasp the theoretical knowledge of books,but also to stimulate students’ interests in scientific research and improve their comprehensive quality.
XIAO Duo-Duo, LI Cui-Yan, XIONG Min-Dong, YE Hua-Qing, ZENG Zhi-Wei, ZHOU Jian-Min. Improvement of Innovative Design Organic Chemistry Experiment of Methylation Reaction[J]. Chinese Journal of Chemical Education, 2022, 43(6): 83-85.
