Abstract By a series of reform measures of optimizing the experimental project, selecting the experimental contents, green materials, solvents and catalysts, promoting the micro or semi-micro experiments, increasing the comprehensive and designable experiments, introducing the new technology, new process and simulation experiments, strengthening the management of the laboratory, reforming the examination pattern, the green teaching in fine chemical experiments was realized, and three wastes pollution in the experiments was reduced. Moreover, the students' awareness of environmental protection was enhanced, the enthusiasm and initiative of the students was mobilized, the creative thinking of the students was trained,and the employment competitiveness was improved at the same time.