Synthesis and Characterization of Anti-HCV Drug Sofosbuvir: Undergraduate “Summer Short Semester” Comprehensive Experiment
CAI Yan1, CAI Guo-Wei1, ZHOU Wei-Hong3, Munira·Abudukeremu2, MIAO Zhi-Wei1,2
1. College of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China;
2. College of Chemistry and Environmental Sciences, Kashgar University, Kashgar 844006, China;
3. College of Life Sciences, Nankai University, Tianjin 300071, China
Abstract This paper introduced the implementation of the "Summer Short Semester" innovative research practice of undergraduates at Nankai University taking the synthesis and characterization of anti-HCV drug Sofosbuvir as an example. The practice involved the background introduction, synthesis and characterization of Sofosbuvir, as well as discussion of experimental results. Practice showed that the comprehensive experiments with a long experiment time and high complexity could improve students' scientific research ability and promote the combination of theoretical teaching and scientific research practice. This approach has achieved a good teaching effect.
CAI Yan, CAI Guo-Wei, ZHOU Wei-Hong, Munira·Abudukeremu, MIAO Zhi-Wei. Synthesis and Characterization of Anti-HCV Drug Sofosbuvir: Undergraduate “Summer Short Semester” Comprehensive Experiment[J]. Chinese Journal of Chemical Education, 2018, 39(14): 31-37.
