Primary Investigation for Thermochemical Principle of in Vivo Oxidation of Glucose
YAN Zi-Hong1, YIN Xue-Bo1,2**
1. College of Chemistry and Environmental Sciences, Kashgar University, Kashgar 844006, China;
2. College of Chemistry, Nankai University, Tianjin 300071, China
Abstract The basis of chemical thermodynamics and three oxidation stages of glucose in vivo are first introduced briefly. Then the thermochemical principles of in vivo oxidation of glucose was revealed. The in vivo and in vitro oxidation of glucose conforms to Hess' Law. The action of enzyme and the energy of ATP increase the number of activated molecules to achieve the in vivo oxidation of glucose at ambient temperature and pressure. The multi-step oxidation of glucose in vivo is helpful to obtain the maximum power, while the multi-step procedure can effectively regulate the release rate of energy in vivo. The first two stages of glucose oxidation in vivo demonstrate that glucose can be adapted to different conditions to provide energy for organisms. The intermediates of different stages also play an important role in life activities. The triple-action of ATP in the in vivo oxidation of glucose is revealed through an extended discussion. ATP is an energy form to increase the number of activated molecules and for energy storage. Moreover, ATP has the characteristics of a catalyst.
YAN Zi-Hong, YIN Xue-Bo. Primary Investigation for Thermochemical Principle of in Vivo Oxidation of Glucose[J]. Chinese Journal of Chemical Education, 2020, 41(12): 23-26.