Abstract This paper systematically examines the evolution of group theory, tracing its development from the foundational concept introduced by Guyton de Morveau in the late 18th century to the functional group theory that emerged following contributions by Berzelius, Dumas, Liebig, and other chemists. Key advancements are detailed, particularly the transition from early empirical approaches to group identification to the establishment of functional group concepts by the end of the 19th century. The paper underscores the pivotal role of functional group theory in elucidating modern organic reaction mechanisms, highlighting its central importance in contemporary chemistry. Additionally, it provides valuable insights for both research and teaching in the history of chemistry.
LIU Yu-Rong, LI Xing-Rong CHEN Xin-Xin. Evolution from Group Theory to Functional Group Theory in Organic Chemistry History[J]. Chinese Journal of Chemical Education, 2026, 47(3): 122-127.