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化学·生活·社会
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| CRISPR-Cas9基因编辑技术的应用与展望 |
| 刘婧, 郑积敏* |
| 北京师范大学化学学院 北京 100875 |
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| Application and Prospect of CRISPR-Cas9 |
| LIU Jing, ZHENG Ji-Min* |
| College of Chemistry, Beijing Normal University, Beijing 100875, China |
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摘要：基因编辑技术是一系列随时间逐步发展演进的技术,先后经历了锌指核酸酶技术、转录激活剂样效应核酸酶技术以及簇状规则间隔短回文重复序列(CRISPR)与其相关蛋白(Cas9)技术。介绍了这些技术的工作原理,探讨了它们各自的优点与不足,重点阐述了CRISPR-Cas9技术在农作物水稻以及医学疾病癌症研究中的应用实例。最后,介绍了人类对基因编辑技术所引发的伦理和社会问题的深切关注。
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| 关键词： 基因编辑,
CRISPR-Cas9系统,
作物改良,
疾病治疗,
伦理问题
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收稿日期: 2024-04-03
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通讯作者:
* E-mail: jimin_z@bnu.edu.cn
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| 引用本文: |
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刘婧, 郑积敏. CRISPR-Cas9基因编辑技术的应用与展望[J]. 化学教育（中英文）, 2025, 46(4): 1-8
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