Abstract The new curriculum standard of chemistry in senior high school advocates combining students' existing experience and the reality of social life to be experienced, guiding students to pay attention to the social problems related to chemistry faced by mankind, cultivating students' sense of social responsibility, participation consciousness and decision-making ability, and emphasizing that teachers should pay attention to the selection and organization of STSE theme content in teaching, and closely connect with the reality of production and life. Guided by the new curriculum standard, this paper combs the situations related to the subject content of STSE in the curriculum standard, and discusses the advanced objectives and different teaching forms of chemistry teaching based on STSE problem-solving with the help of teaching cases.