Abstract Practical training is an important part of cultivating the talented persons in pharmaceutical and chemical engineering in higher vocational colleges. In order to overcome the disconnection between traditional chemical engineering practice teaching and the actual production status of enterprises, we introduced the detailed process of building a semi physical simulation factory including eight process such as nitrification, fluorination, and cyclization, using norfloxacin raw material production as a model carrier, relying on information technology and 3D factory simulation technology. Air, water and neutral solid particles were used to replace real materials. The application of this simulation factory in the integrated teaching practice of theory, virtuality, and reality had achieved good educational results.
TAO Xue-Fen, GONG Shun-Ze, JIN Yin-Xiu, WANG Yu-Xin, KE Zhong-Lu, GUO Jing-Jing. Construction of Pharmaceutical and Chemical Simulation Factory and Its Application in Vocational Practice Teaching[J]. Chinese Journal of Chemical Education, 2024, 45(16): 66-73.