Design of Olefin Meerwein Hydration Reaction Experiment Based on Green Chemistry
HAN Jin-E1, NIU Teng-Fei2**
1. College of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, China; 2. College of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China
Abstract Focusing on the frontier hot spots, implementing the integration of science and education, based on the concept of green chemistry, the comprehensive innovation experiment of olefin Meerwein hydration reaction was designed. In this experiment, photocatalytic synthesis technology was introduced, and a series of 1,2-diphenyl ethanol derivatives were synthesized through alkene Meerwein hydration reaction using the self-made, recyclable catalyst, water as solvent under clean and renewable sunlight. This experiment includes preparation and characterization of the catalyst, synthesis and characterization of products, optimization of reaction conditions, catalyst recycling experiment, and adaptation investigation of substrates. The experiment content is rich and multi-level, involving the cross and fusion of multidisciplinary knowledge, which not only improves students’ comprehensive knowledge application, but also stimulates students’ interest in scientific inquiry and innovative spirit.
HAN Jin-E, NIU Teng-Fei. Design of Olefin Meerwein Hydration Reaction Experiment Based on Green Chemistry[J]. Chinese Journal of Chemical Education, 2024, 45(18): 61-68.
