Project-Based Teaching of “Review of Carboxylic Acids and Their Derivatives” Modifying Drug Molecular Structures Based on Performance Requirements
GAO Ling-Xing1**, PAN Yan-Hong2, ZHOU Shi-Dong3
1. The Ninth Middle School of Horqin District, Tongliao 028000, China; 2. Teaching and Research Section of Tongliao, Tongliao 028000, China; 3. Northeast Normal University, Changchun 130024, China
Abstract This teaching project employs the structural modification of cephalosporin drugs as an instructional context for reviewing the knowledge module of “carboxylic acids and their derivatives”. By analyzing the problem of low antibacterial activity in natural cephalosporin C, students are guided to perform structural modifications on the intermediate 7-aminocephalosporanic acid based on structure-activity relationships. This process enhances students’ problem-solving abilities, deepens their understanding of organic chemistry disciplinary thinking and methods, and fosters the development of a structured knowledge system and disciplinary perspectives.
GAO Ling-Xing, PAN Yan-Hong, ZHOU Shi-Dong. Project-Based Teaching of “Review of Carboxylic Acids and Their Derivatives” Modifying Drug Molecular Structures Based on Performance Requirements[J]. Chinese Journal of Chemical Education, 2026, 47(9): 38-44.
