This paper gives the method of judging the hybridization form of central atomic orbital by the total number of valence electrons of molecule,discusses the theoretical basis of it,and concludes th eperiodic change law of hybridization form of atomic orbital in isoelectronic molecule.

New curriculum whose core is to improve the scientific literacy of students challenges the design of classroom teaching based on fact ,and provides a platform for teaching design based on construc-tion of conception. This paper gives the model of teaching design based on construction of conception,ex-pounds how to carry out teaching design based on construction of conception by the teaching case"ioniza-tion balance",and provides the teaching design of"ionization balance".