化学·生活·社会
操控冰水:仿生抗冻蛋白研究进展*
葛岩, 徐强强, 余卓, 王瑞晨, 沈鑫, 戚震辉**
陕西省柔性电子与健康科学国际联合研究中心 中德空间生物材料与技术转化联合实验室 港澳生物电子与健康工程联合实验室 西北工业大学生命学院 陕西西安 710072
Research Progress of Bioinspired-Antifreeze Protein Materials
GE Yan, XU Qiang-Qiang, YU Zhuo, WANG Rui-Chen, SHEN Xin, QI Zhen-Hui**
Synergetic Innovation Center of Flexible Electronics and Healthcare Science of Shaanxi Province, Sino-German Joint Research Lab of Space Biomaterials and Translational Technology,Synergetic Innovation Center of Biological Optoelectronics and Healthcare Engineering (BOHE),School of Life Sciences, Northwestern Polytechnical University, Xi'an 710072, China
摘要： 抗冻蛋白是自然界娴熟操控(冰)水的分子识别的典范之一。抗冻蛋白的抗冻活性与其特殊结构有着十分密切的关系。作为目前最高效的生物抗冻剂,抗冻蛋白因其含量低、易变性失活,导致产量过低,亟待开发新的来源。近年来,模拟抗冻蛋白的研究工作吸引了科学家们的广泛关注,抗冻蛋白关键的结构特质:氢键作用、疏水性、冰晶吸附、“结构水”在各类仿生抗结冰材料中相继得以体现,对深入理解抗冻蛋白作用机制起到了重要的推动作用。综述了仿生抗冻蛋白在仿生抗结冰材料领域的研究进展,对基于仿生抗冻蛋白的仿生抗结冰材料的发展做出了展望。
关键词： 抗冻蛋白 ,
仿生抗结冰材料 ,
氢键作用 ,
水的分子识别 ,
结构水
基金资助: * 国家留学基金委创新型人才国家合作培养项目(CXXM20190099);2022年西北工业大学高等教育研究基金(国际化人才培养专项)项目(GJGZMS202202); 国家自然科学基金项目(22007078,22071196)
通讯作者:
** E-mail:qi@nwpu.edu.cn
引用本文:
葛岩, 徐强强, 余卓, 王瑞晨, 沈鑫, 戚震辉. 操控冰水:仿生抗冻蛋白研究进展* [J]. 化学教育（中英文）, 2022, 43(12): 11-17
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