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化学·生活·社会
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| 健身运动中的生命化学机理:能量代谢、肌肉重塑与恢复调控* |
| 张四方**, 张世豪 |
| 安徽师范大学化学与材料科学学院 安徽芜湖 241000 |
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| Chemical Mechanisms of Life in Fitness: Energy Metabolism, Muscle Remodeling and Recovery Regulation |
| ZHANG Si-Fang**, ZHANG Shi-Hao |
| College of Chemistry and Material Science, Anhui Normal University, Wuhu 241000, China |
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摘要：从分子化学视角简要概述了健身运动中的能量代谢、肌肉修复以及恢复调控的生化机制,展现出人体在运动应激状态下构建的动态化学网络,旨在从化学视角促进对健身运动的知识普及与认知。
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| 关键词： 健身运动,
分子化学,
糖酵解,
蛋白质,
自由基
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收稿日期: 2025-04-16
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| 基金资助:*安徽省质量工程重点教学研究项目“高校-中学协同下化学师范生科普能力培养的实践研究”(2023jyxm0506);安徽省新时代育人质量工程“化学课堂观察与管理”研究生线下示范课程(2022xxsfkc010) |
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通讯作者:
**E-mail:zhforfine@126.com
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| 引用本文: |
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张四方, 张世豪. 健身运动中的生命化学机理:能量代谢、肌肉重塑与恢复调控*[J]. 化学教育（中英文）, 2026, 47(1): 2-10
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| [1] |
国务院关于印发全民健身计划(2021—2025年)的通知[EB/OL].(2021-08-03)[2024-03-30] .https://www.gov.cn/zhengce/content/2021-08/03/content_5629218.htm
|
| [2] |
夏志,徐飞,陈剑锋,等.生理科学进展,2009,40(4):375-377
|
| [3] |
Hargreaves M, Spriet L. Nat Metab,2020,2(9): 817-828
|
| [4] |
Kelly B, O'Neill L A. Cell Res,2015,25(7):771- 784
|
| [5] |
Owen O E, Kalhan S C, Hanson R W. J Biol Chem,2002,277(34): 30409-30412
|
| [6] |
夏循礼.生物学杂志,2014,31(2):104-108
|
| [7] |
周多奇,龚莉,钱振宇.安庆师范学院学报:自然科学版,2016,22(3):113-118
|
| [8] |
Snow W M, Cadonic C, Cortes-Perez C,et al. Nutrients,2020,12(11):3589
|
| [9] |
Pudney C R, Lane R S, Fielding A J, et al. Journal of The American Chemical Society,2013,135(10): 3855-3864
|
| [10] |
Tae Hun Kim, Pedram Mehrabi, Zhong Ren,et al. Science,2017,355:6322
|
| [11] |
李登光.陕西师范大学学报:自然科学版,2002(1):70-72,77
|
| [12] |
Béard E,Braissant O. J Neurochem,2010,115(2): 297-313
|
| [13] |
Wallimann T, Wyss M, Brdiczka D, et al. Biochem J,1992,281(1): 21-40
|
| [14] |
Bessman S P, Carpenter C L. Annu Rev Biochem,1985,54:831-862
|
| [15] |
Sahlin K, Harris R C, Hultman E.Scand J Clin Lab Invest,1979,39(6): 551-558
|
| [16] |
沈方方,罗娟,金晟娴,等.生命的化学,2007(1):58-61
|
| [17] |
李洪娟,王乐鹏,魏明,等.北京中医药大学学报,2015,38(3):158-161,217
|
| [18] |
贾弘禔, 冯作化. 生物化学与分子生物学. 2版. 北京: 人民卫生出版社, 2010: 165
|
| [19] |
裴利军,陈伟.郑州大学学报:理学版,2009,41(4):1-5,10
|
| [20] |
Pfeiffer T, Schuster S, Bonhoeffer S. Science,2001,292(5516): 504-507
|
| [21] |
Goldbeter A L, Lefever R. Biophysical Journal,1972,12:1302-1315
|
| [22] |
Hess B, Boiteux A. Annual Review of Biochemistry,1971,40: 237-258
|
| [23] |
张慧芳,曾志军,周艳宏.生物化学与生物物理进展,2021,48(2):147-157
|
| [24] |
Gao H, Arner P, Beauchef G, et al. Cell Metab,2020,32(1): 1-3
|
| [25] |
Teusink B, Passarge J, Reijenga C A, et al. European Journal of Biochemistry, 267(17):5313-5329
|
| [26] |
刘雪云,李高权,徐守宇.中国运动医学杂志,2013,32(7):654-657,632
|
| [27] |
Ventadour S,Attaix D. Curt Opin Rheumatol,2006,18(6):63l-635
|
| [28] |
郑东东.细胞生物学杂志,1996(2):68-73
|
| [29] |
Karagounis L G,Yaspelkis B B,Reeder D W,et al. Eur J Appl Physiol,2010,109(5):839-848
|
| [30] |
Vijayaraj P,Kroger C,Reuter U,et al. J Cell Biol,2009,187(2):175-184
|
| [31] |
Laplante M, Sabatini D M. mTOR Signaling in Growth Control and Disease Cell,2012,149(2): 274-293
|
| [32] |
Inoki K, Li Y, Xu T,et al. Genes & Development,2003,17(15):1829-1834
|
| [33] |
Huang Jingxiang, Manning Brendan D. Biochem J,2008,412 (2): 179-190
|
| [34] |
Sancak Y, Peterson T R, Shaul Y D,et al. Science,2008,320(5882):1496-1500
|
| [35] |
Wolfson R L, Chantranupong L, Saxton R A, et al. Science,2016,351(6268):43-48
|
| [36] |
Wang Y J, Bian Y, Luo J,et al. Nat Cell Biol,2017,19(7): 808-819
|
| [37] |
Ferreira L T, Orr B, Rajendraprasad G,et al. J Cell Biol,2020,219 (4): e201910064
|
| [38] |
Jacinto E, Facchinetti V, Liu D,et al. Cell,2006,127(1):125-137
|
| [39] |
Yang H R, Wang J, Liu M J,et al. Protein & Cell,2016,7(12): 878-887
|
| [40] |
秦本源,李步高,曹果清.中国生物化学与分子生物学报,2019,35(2):113-120
|
| [41] |
陈明辉,占琦,霍光华.生命的化学,2005(3):193-195
|
| [42] |
Stadtman E R. Free Radic Res,2006,40(12):1250-1258
|
| [43] |
Hartl FU, Hayer-Hartl M. Nat Struct Mol Biol,2009,16(6):574-581
|
| [44] |
Mayer M P, Bukau B. Cell Mol Life Sci,2005,62(6):670-684
|
| [45] |
Njemini R, Bautmans I, Onyema O O, et al. BMC Immunol,2011,28:12-24
|
| [46] |
Annemans L, Nackaerts K, Bartsch P, et al. Clin. Drug Investig,2009,29(10):655-665
|
| [47] |
Saibil H. Nat Rev Mol Cell Biol,2013,14(10):630-642
|
| [48] |
Murphy M P. Biochem J,2009,417 (1): 1-13
|
| [49] |
Bedard K,Krause K H. Physiological Reviews,2007,87(1): 245-313
|
| [50] |
Sies H. Redox Biology,2017,11: 613-619
|
| [51] |
Fridovich I. Annual Review of Biochemistry,1995,64: 97-112
|
| [52] |
Chelikani P, Fita I, Loewen P C. Cell. Mol. Life Sci,2004,61(2): 192-208
|
| [53] |
Brigelius-Flohé R, Maiorino M. Biochimica et Biophysica Acta (BBA)-General Subjects, 2013,1830(5): 3289-3303
|
| [54] |
Paulsen C E, Carroll K S. Chemical Reviews,2013,113(7): 4633-4679
|
| [55] |
Holmgren A, Johansson C, Berndt C,et al. Biochem Soc Trans,2005,33 (6): 1375-1377
|
| [56] |
Tonelli C, Chio IIC, Tuveson D A. Antioxidants & Redox Signaling, 2018,29(17): 1727-1745
|
| [57] |
Itoh K, Wakabayashi N, Katoh Y,et al. Genes & Development,1999,13(1): 76-86
|
| [58] |
Chung K W, Dhillon P, Huang S Z,et al. Cell Metabolism,2019,30(4): 784-799
|
| [59] |
Liu F, Yuan Y, Bai L,et al. Redox Biology,2021,43:101963
|
| [60] |
Bepler T, Kelley K, Noble A J, et al. Nat Commun,2020,11:5208
|
| [61] |
Norton L E, Layman D K. Journal of Nutrition,2006,136(2): 533S-537S
|
| [62] |
Phillips S M, Tang J E, Moore D R. Journal of the American College of Nutrition,2009,28(4): 343-354
|
| [63] |
杜维根,白磊阳,姜雪峰.化学教育(中英文),2025,46(10):1-9
|
| [64] |
Jeukendrup A. Sports Med,2014,44(1): 25-33
|
| [65] |
Gibson G R, Hutkins R, Sanders M E,et al. Nat Rev Gastroenterol Hepatol, 2017,14(8): 491-502
|
| [66] |
St-Onge M P, Jones P J H. Journal of Nutrition, 2002,132(3): 329-332
|
| [67] |
Calder P C. Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids,2015,1851(4): 469-484
|
|
|
|
