Abstract Building on the bimolecular nucleophilic substitutions (SN2, herein denoted as SN2C) of haloalkanes, we introduce the halogenophilic substitutions (SN2X). The theoretical analysis with molecular orbital theory, factors that govern the reactions, and some representative SN2X reactions are covered. This paper serves as a deep extension and complement to the fundamental textbooks.
YANG Zhan-Hui, CHEN Ning. Theoretical Basis and Govern Factors ofHalogenophilic Substitutions of Haloalkanes[J]. Chinese Journal of Chemical Education, 2023, 44(6): 103-108.
