Abstract The problem-chain instructional approach,characterized by logically coherent and hierarchically structured questions,is designed to foster students’ critical thinking and promote deep knowledge integration.Taking the teaching unit on the“Competition between Nucleophilic Substitution and Elimination Reactions of Haloalkanes”as a case study,this paper systematically develops a problem-chain teaching framework and its implementation strategy for organic chemistry courses.By incorporating six types of problem chains involvingstimulating,comparative,transferable,adaptive,diagnostic,and progressive,the approach guides students to explore the competition and controlling factors between substitution and elimination reactions from multiple perspectives,including reaction mechanisms,stereochemistry,and regioselectivity.This mode not only increases student engagement and improves knowledge synthesis but also strengthens students’ abilities in logical reasoning,systems thinking,and solving complex chemical problems,thereby supporting effective teaching and learning in organic chemistry.
HU Xin, ZHENG Jie, MAO Liu-Liang, LIU Feng, JI Cong-Bin. Problem-Chain Teaching Mode in Organic Chemistry:Competition Between Nucleophilic Substitution and Elimination Reactions of Alkyl Halides[J]. Chinese Journal of Chemical Education, 2026, 47(10): 19-24.