Whether we feel happy or sorrow, positive or negative, excited or tired, it seems all depends on who we meet or what we come across. Nonetheless, it is actually an expression from a series of chemical substances and chemical transformation in human body produced due to external incentives and atmospheric stress, from the perspective of the interaction of life substances. Compounds such as hormones and neurotransmitters (chemical messengers) cause certain emotions that we feel when triggered by external events. The generation of different sentiments will further stimulate the secretion of corresponding substances in the body. Antipodal, transformation and tracing relations between various emotions and relating chemical molecules are discussed comprehensively in this paper.

Antifreeze protein is one of the models of molecular recognition that skillfully manipulates (ice) water in nature. The antifreeze activity of antifreeze protein is closely related to its special structure. As the most efficient biological antifreeze at present, antifreeze protein has low yield due to its low content and variable inactivation, so it is urgent to develop new sources. In recent years, the research of simulated antifreeze protein has attracted extensive attention of scientists. The key structural characteristics of antifreeze protein: hydrogen bonding, hydrophobicity, ice crystal adsorption and structural water have been reflected in various bioinspired anti-icing materials, which have played an important role in deeply understanding the functional mechanism of antifreeze protein. In this paper, the research progress of bioinspired antifreeze protein mimics is reviewed, and the development of antifreeze protein and their biomimetic is prospected.

Engineering chemistry is a characteristic and important chemistry course for undergraduates majoring in non-chemistry or chemical engineering, which is a bridge between chemistry and engineering technology, and an integral part of knowledge, ability and quality system of application-oriented undergraduates education. In the ever-changing and new period of history, engineering chemistry education is faced with the challenges of globalization, popularization and informationization. More importantly, the engineering chemistry course for freshmen plays a very important role in carrying out the fundamental task of establishing moral integrity in cultivation in colleges and universities. Textbook is the important carrier of education. The new era puts forward new challenges and requirements for the construction of engineering chemistry textbook. This paper introduces the exploration and practice of multi-dimensional and long-term construction of engineering chemistry teaching materials in Beijing Jiaotong University under the background of the new era.

Ideological and political education is an important way for universities to play the role of morality construction and talent cultivation, and it is also an important starting point to improve the “San Quan” education. Chemistry is one of the fundamental research, which is of great significance to improve the innovation ability. Therefore, the premise of incorporate ideological and political education into the education of chemistry is curriculum construction. Nowadays, problems including imperfect education system and backward teaching level in ideological and political education, still exist in the introduction course of chemistry. In this paper, the construction of ideological and political education in chemistry was explored by practicing the introduction course of chemistry in the School of Chemistry and Chemical Engineering of Huazhong University of Science and Technology, in which the curriculum design and teaching methods was improved. By analyzing the significance and difficult issues of ideological and political education in chemistry course, a program was proposed to construct the introduction course, and an effective system of ideological and political education in chemistry teaching was established.

It is requirement for the cultivation of contemporary innovative talents to construct innovative, high-level and challenging “golden course”. University chemistry is a basic course of non-chemical science and engineering majors in our university. Compared with mathematics and physics, students pay less attention to it, resulting in unsatisfactory teaching effect. In order to solve this problem, a student-oriented hybrid teaching mode is adopted. By setting basic, applied and innovative problems, students are guided to solve them to improve their active participation. The applied questions include the frontier of science and technology, professional application, social hot issues, etc., which can increase the depth and breadth of the content to stimulate students' interests in exploration. By designing experimental scheme and experimental test, students' innovative thinking can be cultivated. The cumulative method is adopted to evaluate the teaching effect, and the practice results show that the hybrid teaching mode can significantly improve the students' independent learning ability and interest, and improve the teaching effect.

On basis of the course features of inorganic chemistry in our school, the objectives of course ideology and politics were drafted, and the contents of the course were correspond to the ideology and politics elements. The ideology and politics elements were integrated into the resource platform (MOOC platform), teaching platform (Chaoxing Learning APP), and service platform (WeChat Official Accounts) of inorganic chemistry, and a “three-in-one” method of course ideology and politics with explicit and implicit combination was constructed through innovative teaching. It provided a reference for the course ideology and politics of other professional courses.

Esterification reaction is the most important type of experiment in organic chemistry teaching experiment. Different methods of ester synthesis are quite different, which can cultivate students' practical ability. Based on the teaching experiment, this paper investigates the esterification of salicylic acid and isoamyl alcohol. Isoamyl salicylate is a product with broad prospects and great development value. Studying its synthesis method has great potential economic benefits and social benefits. Isoamyl salicylate was synthesized by water fractionation with cyclohexene as water carrying agent. The yield was 85.9%. By studying the synthetic method of isoamyl salicylate, the students' innovative ability of independent thinking and the scientific spirit of exploration were cultivated, and good teaching effect was achieved.

In order to meet the requirement of cultivating innovative talents, comprehensive chemical experiment course should be set up for senior undergraduates, aiming at cultivating students' ability of comprehensive knowledge application and accomplishment of scientific research. Taking the experiment “preparation of carbon quantum dots and their application in quantitative analysis of tetracycline” as example, through literature review, method study, performance testing, and results analysis, students can master the preparation technology of nanomaterials, instrumental characterization and general steps of quantitative analysis of complex samples, etc. The course content joints scientific frontier spots and curriculum design takes the students as main body. The teaching mode oriented by “need” and “problem” is helpful to stimulate students' interests and cultivate their innovative practical ability.

Sulfonic acid ionic liquids and polyoxometalate catalysts are two kinds of efficient and environment-friendly catalysts and have been widely applied in the organic reactions in recent years. The assembly of two kinds of catalysts into one component bifunctional environmental catalysts to replace the strong corrosive and strong oxidizing concentrated sulfuric acid is the direction of future organic experiment reform. [PIMPS]H₂PW₁₂O₄₀ (PIMPS=1-propyl-3-sulfopropyl imidazolium sulfonate) catalyst was synthesized and characterized by ¹H NMR and IR, and then the catalyst was applied to the synthesis of ethyl benzoate and the oxidation of thioanisole. The results showed that the catalyst has the bifunction properties of acid catalysis and oxidation catalysis and exhibited the efficient catalytic activities, which can be reused in the reactions. Additionally, it has the characteristics of homogeneous and heterogeneous catalyst, which can realize homogeneous reaction and heterogeneous recovery in esterification and thioanisole oxidation reaction. Through the training of this experiment, the students' innovative ability to find and solve problems based on the concept of green chemistry is cultivated. It is helpful for students to deeply understand the concept of single component bifunctional catalyst and achieve the organic combination of theory and practice.

In this popular science experiment, gutter oil and bentonite were used as the main raw materials to prepare decontamination soap through saponification reaction. The main purpose of this project includes simplifying the purification process of gutter oil, optimizing the formula of saponification reaction, beautifying the products, and enhancing the ornamental and interactive nature of the experiment. Further, the purification process of gutter oil, saponification phenomenon, and the chemical principles behind it were comprehensively and stereoscopically displayed to the public through different ways, including videos, brochures, and experiencing activities.

The education and teaching ability system of normal university students is refined based on Standard of Teachers' Professional Ability of Normal University Students Majoring in Middle School Education, and the system covers the competency of ethics practice, practical teaching ability, comprehensive education ability and professional development ability and the corresponding 10 aspects of ability elements. Taking chemistry teaching theory as an example, this paper analyzes the corresponding relationship between the contents of the chapter and the four abilities,and discusses the formation mechanism and ways of education and teaching ability of chemistry normal students in the course implementation. The formation mechanism of the four ability of chemistry normal students has its own characteristics, which requires positive interaction between normal students and teachers.

The construction and practice process of the key education course for chemistry teacher, chemistry instructional design and execution, was presented in this paper. Aimed for training chemistry core teachers for middle school, the objectives of this course have been reformed and established based on OBE (outcome-based education) concept. It included setting the teaching goal around the design model of “literacy-based” chemistry teaching, arranging teaching materials, strategizing teaching methods and finally adopting multiple evaluation. All these schedules would precisely improve pre-service teachers' indispensable literacy in their future career. The results demonstrated that the teaching reform had been successfully realized and recognized by the national peers, which makes progress in teaching and learning. Finally, the shortage and the future outlook of this course were discussed, as well as the improvement measure was further put forward.

Taking “acid-base titration method” as an example, based on the self-created SPOC curriculum resources for the students majoring in pharmacy, online and offline blended teaching mode including front analysis, teaching process and evaluation method is constructed. With full analysis of teaching content, object, learning status and learning environment, the teaching process consisting of three procedures of preview before class online, classroom teaching offline and extended study after class online is properly designed. The diversified and comprehensive assessment combining online and offline evaluation is developed with the improvement of process evaluation. Through the reflection of the whole process of teaching, the main advantages and problems of online and offline blended mode in the teaching of analytical chemistry are discussed.

In order to build a high-level, innovative, and challenging first-class main course to adapt the requirement of new era, and realize the education and teaching goals of value guidance, ability training, and knowledge transfer, combining the characteristics of the functional materials major with the academic conditions of the students in the national colleges and universities, we constructed a new blended teaching mode of “four modules, three stages, two time and space, and two platforms” for physical chemistry course, and reconstructed the “four modules” content of “value leading module, basic theory module, multidisciplinary integration module, virtual simulation experiment module” system. Through the “four modules” embedded in the blended teaching practice, combing with the students' pre-class, in-class, and after-class performance to evaluate the learning effect in multiple dimensions, and by questionnaires to analyze the students' evaluation of the blended teaching, the final research results show that the students' individualized autonomous learning ability has been significantly improved, the comprehensive ability of the students to solve complex problems with the theory of physical chemistry has been improved, and the students have gained a sense of accomplishment through hard work.

Taking the constructed framework of elements of nature of science as an analysis tool, this paper studies the view of the nature of science presented by students through popular science micro video analysis. The results show that they can not comprehensively and deeply analyze the presented nature of science by the videos, which reflects the limited view of nature of science, and the discussion and report can promote their understanding of nature of science. Therefore, three suggestions are put forward for the training of master of chemical education, including taking popular science micro video as the material of science essence education, promoting students to form a complete and profound view of nature of science, and developing students' ability to accurately extract the nature of science in curriculum resources.

It is the important basis of title and abstract to be downloaded and read for paper. Therefore, it is of great significance for normalization expression in the writing of the title and abstract. Combined with practical cases, the common problems in the writing process of title and abstract of chemical analysis scientific papers and its corresponding attentions are proposed.It is indicated that the title could be embellished by referring to three elements, including method, material and element (or component) fordetermination.The title could be normalized from three aspects: accuracy and specificity, highlighting innovative content and facilitating retrieval. The writing method of abstract is discussed from three logical levels, such as problem statement at the beginning (or significance for determination), research content in the middle, and results at the end. Simultaneously, the important research content or innovation points should be highlighted.

Herein the construction and practice of molecular point group virtual laboratory (PGVL) is reported in molecule symmetry part of structural chemistry course, which is used to help students deeply understand and master the research methods and basic knowledge of molecular symmetry. The PGVL simulation experiment is constructed by web technology and supports the display and interaction of molecular models. Students could complete various symmetrical operations of molecules, point out symmetrical elements in molecular structure, deduce molecular point groups, and understand the relationship between molecular structure and properties. The application of PGVL platform in molecular symmetry could not only improve the practical teaching of molecular symmetry of structural chemistry, but also encourage students' interests in this field. PGVL enriches the teaching system in molecular symmetry of structural chemistry and achieves good teaching effect.

In order to promote the effect of flipped classroom teaching of organic chemistry in colleges, an assistant teaching software system of organic chemistry based on mobile augmented reality technology is designed and implemented. The system is consist of an mobile client which can be used to observe compound molecules by AR mode and to browse all kinds of teaching resources by students, and a PC client for teachers to edit the knowledge system of teaching materials, to upload 3D models of compound molecules and multimedia resources. The system is applied to flipped classroom teaching and experiments are carried out to study its teaching effect from three aspects: achievement comparison, questionnaire survey and student interview. The results show that the use of the system plays a positive role in promoting students' interests in learning and achieves better teaching results in flipped classroom teaching. And this provides a demonstration and reference for the design and implementation of the teaching reform of the same type of courses in colleges and universities.

Colloidal particles are a very important research object in natural science. Due to the effect of gravitational potential field, colloidal particles are not uniformly distributed (assuming Boltzmann distribution). In order to investigate the influence of Boltzmann distribution on the test results, the Boltzmann distribution of silica with three particle sizes (20 nm, 50 nm and 100 nm) under the effect of gravitational potential field is discussed by theoretical calculation, that is, the variation of concentration with height, and compared with the average concentration. The results show that the larger the particle, the greater the influence of gravity potential field on particle distribution, and the greater the error of test results. Finally, through theoretical calculation, this paper points out that reasonable selection of particle type and particle size can reduce the influence of Boltzmann distribution on the test results.

Due to the differences in curriculum settings and academic characteristic of students, the PBL teaching mode has its own unique feature in the implementation of chemistry experiment courses in Chinese and American universities. This paper objectively analyzes the differences in the application of the PBL teaching mode in the chemical experiment courses in Chinese and the American universities from four perspectives: teaching material, curriculum assessment, teacher training, research institutions and funding, on this basis, this article proposes that we should treat this difference objectively and fairly, and build cultural confidence.