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Chinese Journal of Chemical Education  
  Chinese Journal of Chemical Education--2025, 46 (18)   Published: 18 September 2025
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Chinese Journal of Chemical Education. 2025, 46 (18): 0-0.
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Chinese Journal of Chemical Education. 2025, 46 (18): 117-117.
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Chemistry-Life-Society

Chemical Education in the Age of Artificial Intelligence:Opportunities, Challenges,and Talent Development

ZHAO Wei-Guang
Chinese Journal of Chemical Education. 2025, 46 (18): 1-9. ;  doi: 10.13884/j.1003-3807hxjy.2025020040
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With the rapid advancement of artificial intelligence(AI)technology,the application of AI,represented by ChatGPT,in the field of chemical research has achieved numerous groundbreaking progresses.These advancements span across various domains including deep learning,big data and integrated data,automated laboratory platforms,and simulation and modeling,significantly enhancing the efficiency of scientific research.In chemical education,AI technology has already been implemented through virtual laboratories and adaptive learning platforms,greatly enriching teaching methodologies.However,the application of AI in the field of chemistry has also revealed several issues,such as computational errors,conceptual confusion,and the fabrication of references and content.Additionally,AI poses potential risks of diminishing students' logical thinking and writing abilities,and it has limitations in fostering original innovation.Therefore,in the era of AI,while strengthening the foundational theoretical education of students,chemical education should place greater emphasis on guiding students to think independently,cultivating their observational skills,judgment abilities,logical thinking,and stimulating their interest and curiosity,thereby nurturing their innovative thinking capabilities.

Research Progress on Compounds of the Noble Gas Element Helium

REN Jian-Lin, LI Bing, LIU Xiang-Yu, CAO Bao-Yue, KE Zeng-Bo, GAO Sheng-Li
Chinese Journal of Chemical Education. 2025, 46 (18): 10-22. ;  doi: 10.13884/j.1003-3807hxjy.2024100154
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The noble gas(Ng)element helium has a 2-electron closed shell structure and extremely strong chemical inertness,making it very difficult to combine with other elements to form compounds.However,this characteristic is not absolute.With the change of reaction conditions,such as under high temperature and high pressure,it can still form bonds with other elements.Many helium compounds that may stably exist are also predicted by advanced quantum chemical calculations.On the basis of the original,this paper attempts to introduce the synthesis research progress of helium compounds from the perspective of chemical bonds,that is,how to form local chemical bonds,hydrogen bonds and-range van der Waals forces.
Curriculum-Teaching Materials-Assessment

Development of First-ClassOrganic ChemistryCurriculum in Local Universities in the“Internet+”Era

FAN Yan-Qing, ZENG Jing, LI Jia-Jia, LI Xiao-Juan
Chinese Journal of Chemical Education. 2025, 46 (18): 23-29. ;  doi: 10.13884/j.1003-3807hxjy.2025010124
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In the era of“Internet+”,local universities encounter novel demands and challenges in the development of first-class courses.Taking the Organic Chemistry course at Xinjiang Normal University as a case study,this paper investigates the strategies for developing a first-class course within this context.By forming an innovative teaching team,enriching both online and offline teaching resources,developing diverse and integrated teaching modes and methods,and establishing a comprehensive evaluation system,the institution can better meet the individual needs of students,foster their innovative capabilities,reshape classroom teaching formats,and achieve the goal of student-centered education.The research findings and practical outcomes of this paper offer valuable references and insights for the development of first-class courses in regional universities.

Meaning, Contents and Measures of Chemical Science Popularization in University

LIU Hai-Yan, DING Qiong, HU Kai, ZHANG Hai-Bo, WU Xiao-Jun, YANG Ying, LIU Yu-Wen, ZHAO Fa-Qiong
Chinese Journal of Chemical Education. 2025, 46 (18): 30-35. ;  doi: 10.13884/j.1003-3807hxjy.2024120079
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National demonstration center for experimental chemistry education of Wuhan University is dedicated to explore and practice of chemical science popularization.By developing science popularization activities and new chemical experiments to enrich the content and a more suitable way.Relying on the existing advantageous resources and technological support conditions of Wuhan University,we will leverage the leading and radiating role of national demonstration center.
Theory Teaching

Teaching Innovative of Instrumental Analysis Course from the Perspective of Different Learning Roles:Atomic Absorption Spectroscopy

BO Xiang-Jie, CHEN Xue-Xin, ZHANG Hong-Ling
Chinese Journal of Chemical Education. 2025, 46 (18): 36-41. ;  doi: 10.13884/j.1003-3807hxjy.2024120103
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In the teaching of instrumental analysis,it still faces several challenges,including limited interdisciplinary learning skills,difficulties in integrating theory with practice,an inability to apply the knowledge to solve real-world problems,and lack of foresight regarding the future development of instruments.Taking atomic absorption spectroscopy as an example,students cultivate interdisciplinary thinking by assuming the role of the“creator”of atomic absorption analysis methods,inspiring more innovative ideas.As the“designer”of the atomic absorption spectrometer,students try to design “simple” instruments to gain a deep understanding of the structure and operation principles of the instrument.In the role of“user”,students explore the latest applications and advancement in instrument development,learning to address practical problems with the instrument.Lastly,by envisioning the future development trend of the instrument as the “visionary”,students foster innovation and explore emerging technologies,cultivating global perspectives and a spirit of innovation in future talents.By adopting these four different roles,students gain a comprehensive understanding of the creation,design,application,and future trends of atomic absorption spectrometers from a higher perspective.This instructional design not only enhances students' interdisciplinary thinking and knowledge acquisition but also improves problem-solving ability.Meanwhile,it aims to nurture innovative talents with forward-looking views.

Innovative Application of Knowledge Map and Large AI Models in the Teaching of Transition State Theory in Physical Chemistry

ZHANG Xin, ZHANG Shi-Long, FENG Hai-Song, XU Xiang-Yu, YU Le, LIN Chang-Gen, LI Le-Yuan, CHEN Xing-Quan
Chinese Journal of Chemical Education. 2025, 46 (18): 42-48. ;  doi: 10.13884/j.1003-3807hxjy.2025010227
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This study explores a teaching mode for physical chemistry that integrates knowledge map with AI large models,aiming to enhance students' understanding and application ability of transition state theory.The course adopts a comprehensive design of “pre-classb-in-class-post-class”.Before class,students use knowledge map and AI large models to preview fundamental concepts.During class,the alkaline hydrolysis of ethyl acetate is used as an example,where computational chemistry software simulates the reaction mechanism,vividly presenting the dynamic reaction process.The teacher explains the theory and guides the operations.After class,students reinforce their knowledge through summarization and training with knowledge map and AI large models.The initial teaching practice indicates that 90% of students can successfully complete the course content,though they face difficulties in software operation and interacting with AI large models.While this mode relies heavily on technology,it significantly improves students' understanding and application ability of transition state theory,stimulates learning interests and innovative thinking,and has the potential to serve as a mode for teaching in this field.
Experiment Teaching

Internationalization Exploration and Resource Construction of Physical Chemistry Experiment Teaching

XU Yi-Meng, ZHOU Xuan, Ali Bahadur
Chinese Journal of Chemical Education. 2025, 46 (18): 49-56. ;  doi: 10.13884/j.1003-3807hxjy.2025010195
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Education internationalization is a crucial pathway for building a powerful country in higher education,Sino-foreign cooperative education is a significant window for international collaboration and exchange in education.Addressing the differences in course content and experiment design of Chinese and foreign physical chemistry experiment teaching,this study integrates strengths from both systems,combined with actual situation,an English lab manual was developed.The equipment was optimized via industry-academia collaboration to align experimental designs.And corresponding digital teaching resources and a virtual simulation experiment platform were established.These efforts aim to create a fully immersive English-language experimental environment and explore the implementation of internationalized physical chemistry experiment teaching,with the ultimate goal of cultivating highly specialized talents with global competitiveness.

Jilin University's Holistically Integrated Practice-Education System for Cultivating Innovative Talents in Chemistry

LI Ya-Jie, GUO Yu-Peng, WEI Shi-Gang, YAN Jin
Chinese Journal of Chemical Education. 2025, 46 (18): 57-64. ;  doi: 10.13884/j.1003-3807hxjy.2025040221
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This paper addresses the growing demand for cultivating innovative chemistry talents in the new era by proposing an integrated practice-education system designed to overcome the limitations of conventional models,including fragmented curricula,the research-education disconnect,and unsustainable pedagogical frameworks.Grounded in synergistic approaches,the system emphasizes curriculum optimization to bridge disciplinary boundaries,deep integration of scientific research with teaching practices,establishment of multi-tiered platforms for cross-institutional resource sharing,and proactive cultivation of safety awareness in experimental training.Empirical results demonstrate that this holistic framework facilitates a progressive transition from foundational laboratory competencies to advanced innovative capabilities,offering the “Jilin University Paradigm” as a scalable solution for chemistry education reform.The mode has significantly enhanced students' critical thinking and interdisciplinary problem-solving skills,aligning with national strategic priorities for high-caliber chemistry professionals.Its effectiveness is evidenced by widespread adoption and recognition across domestic and international academic communities.

Synthesis of Nitrendipine by Four-Component One-Pot Solvent-Free Reaction: Green Organic Chemistry Teaching Experiment Design

XU Ruo-Yang, MA Xiu-Ya, GU Li-Ji, ZHANG Yan, QIU You-Ai
Chinese Journal of Chemical Education. 2025, 46 (18): 65-71. ;  doi: 10.13884/j.1003-3807hxjy.2025010203
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Multicomponent reactions have become an important representation of green organic synthesis due to their simplicity,efficiency,and step economy.However,current university organic chemistry textbooks generally lack content on multicomponent reactions.Nitrendipine,a widely used drug for the treatment of hypertension,contains the important heterocyclic structure of 1,4-dihydropyridine.This paper presents an innovative teaching experiment,“four-component one-pot solvent-free synthesis of nitrendipine”,and applies it to a short-term innovation experiment course for second-year undergraduate chemistry students.The synthesis uses cheap and readily available starting materials m-nitrobenzaldehyde,methyl acetoacetate,ethyl acetoacetate,and ammonium acetate to efficiently prepare nitrendipine through a“one-pot”reaction.This experiment offers several advantages,including a short reaction time without solvents and catalysts,and the visibility of significant experimental phenomena.

Experimental Teaching Design for Preparation of Double-Emission Fluorescent Nanomaterial and Visual Detection of Tetracycline

HUANG Shu-Ting, ZHAO Ya-Xuan, XIAO Yang, LIN Bi-Xia
Chinese Journal of Chemical Education. 2025, 46 (18): 72-77. ;  doi: 10.13884/j.1003-3807hxjy.2025010205
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Fluorescence method is a very important experiment in instrumental analysis experiments,and it is an analytical technology that must be mastered by chemistry,environment,food,materials and other majors.At present,the experimental content of fluorescence analysis in most teaching textbooks is thin and the experimental procedure is single.As a supplement to the current teaching content,an innovative experiment of ratiometric fluorescence method for visualization and real-time detection of tetracycline is designed combining with the research hotspot in the forefront of analytical chemistry.The experiment includes one-step synthesis of double-emission Eu3+ modified silicon nanoparticles(Eu@SiNPs),establishment of ratiometric fluorescence detection method,preparation of test strips,detection of actual samples,etc.Through this experiment,on the basis of consolidating students' professional theoretical knowledge and practical ability,the students' scientific research thinking and comprehensive ability to analyze and solve problems are further cultivated,so as to achieve the purpose of innovative experiment teaching.
Vocational Education

Practice Teaching Curriculum System of Chinese Pharmacy Specialty Based on Training of Innovative Talents

WU Xin, HUA Zheng-Ying, NIU Min, DENG Xiang-Min, LIU Xu
Chinese Journal of Chemical Education. 2025, 46 (18): 78-86. ;  doi: 10.13884/j.1003-3807hxjy.2024120142
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To address the urgent shortage of innovative talents in the traditional Chinese medicine pharmaceutical industry under the background of transformation and upgrading, this study focuses on cultivating applied innovation capabilities. We construct an open, multi-tiered practical curriculum system that systematically integrates foundational training, verification training, comprehensive training, project-based training, innovation extension, and internship components. The study further enhances this system's content framework while investigating an innovative three-dimensional open practical teaching mode. We have developed collaborative school-enterprise practice bases, created systematically integrated training modules, and instituted a multi-dimensional teaching evaluation system. These strategies significantly improve students' comprehensive application competencies and practical innovation levels, providing robust support for cultivating innovative technical-skilled talents.
Chemical Education for Non-Chemistry Majors

Practice of 3E Talent Training in Salt Industry Under the Context of Quality-Driven Development Strategy: The Case of Salter Teaching Paradigm

DU Wei, LI Rui-Ning, HAO Qing-Lan, ZENG Wei, JIA Yuan-Yuan, TANG Na
Chinese Journal of Chemical Education. 2025, 46 (18): 87-94. ;  doi: 10.13884/j.1003-3807hxjy.2024110078
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In the context of Quality-Driven Development Strategy,excellent engineering talents with job competency(Engineering,Expertise,Excellent,referred to as 3E)are adapted to the requirements of the development of new quality productivity.Aiming at the three pain points of engineering talent training,which are not new engineering knowledge,incomprehension of engineering problems and lack of engineering emotion,it puts forward the teaching concept of“green intelligent creation,true practice and deep experience”in this study.Salter teaching paradigm,which contains course content reconstruction and extension(Stretch),resource scenario creation and association(Associate),seven-ring link teaching mode creation(link),salt industry post depth experience(Taste),multiple evaluation and positive feedback(Evaluate),ideological and political guidance and emotional resonance(Resonance),have been conducted in-depth.The exploration and practice of Salter teaching paradigm has realized the hierarchical training of 3E talents.After years of practice,many high-level engineering and technical talents have been cultivated for the salt industry,forming a new paradigm for the cultivation of 3E talents in the salt industry under the strong quality country,and leading the innovation and development of the salt industry.

Long-Term Teaching Management Mechanism for Polymer Materials and Engineering Based on Engineering Education Accreditation Principles

HE Yu-Cheng, WANG Ying, ZHOU Shuai, XIANG Bo, LEI Wen, LUO Zhen-Yang, SHA Ye
Chinese Journal of Chemical Education. 2025, 46 (18): 95-99. ;  doi: 10.13884/j.1003-3807hxjy.2024110137
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Within the framework of continuous improvement in engineering education accreditation,“curriculum teaching and assessment” is a critical component for implementing the OBE(Outcome-Based Education)philosophy,yet it commonly suffers from declining effectiveness in policy execution.Addressing issues such as poor policy coordination across the university,college,and program levels,excessive assessment workload for teachers,and delayed academic warnings,this study develops a multi-level digital monitoring and management system using the polymer materials and engineering program at Nanjing Forestry University as a case study.The aim is to explore a sustainable mechanism for accreditation management.Specifically,the system assigns responsibility entities and completes multi-level reviews on a digital platform to ensure the operational level of various management systems.It also automates the scanning of examination papers,breaks down questions,and intelligently generates course quality reports,thereby alleviating the evaluation burden on teachers.Additionally,it quantifies the progress of “formative assessments” and creates a radar chart for each student to track their progress in meeting graduation requirements,enabling timely academic warnings and support.This mechanism provides strong assurance for students to meet graduation requirements and offers a scalable digital solution for the routine operation of engineering education accreditation.

Organic Chemistry Blended Teaching Design Based on Problem Oriented “ADDIE”Mode:Cis-Trans Isomerism

ZHANG Jin, DONG Li
Chinese Journal of Chemical Education. 2025, 46 (18): 100-109. ;  doi: 10.13884/j.1003-3807hxjy.2024120220
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Organic chemistry is a core compulsory course for pharmacy majors in medical schools.In order to solve the problems of short hours,numerous knowledge points and low learning enthusiasm of students in organic chemistry under the traditional mode,the online+offline blended teaching process was redesigned based on the ADDIE mode.Taking“cis-trans isomerism”as an example,this paper sets up five guiding questions around the main line of“structure determines properties,properties determine uses”,and drives students' independent learning before class,interactive learning during class,and consolidation and sublimation after class.Combined with life situations and drug cases,a variety of teaching methods are used to guide students to“move from life to chemistry and explore chemistry from cases”to stimulate students' initiative in learning.Multi-dimensional evaluation methods are used to optimize teaching design and promote students' high-quality participatory learning.
Information Technology and Chemistry

Smart Chemistry Classrooms in University Empowered by Supercomputing Mode Based on Combination of Computational Simulation Software and Supercomputing Platform

YAO Yuan, LIU Yang, ZHAO Mei-Yu
Chinese Journal of Chemical Education. 2025, 46 (18): 110-117. ;  doi: 10.13884/j.1003-3807hxjy.2025020025
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In the era of “intelligence+”,higher education is in a critical period of high-quality improvement,and it is of great significance to construct a smart classroom teaching mode with human-computer interaction for undergraduate and graduate students in universities.In the present study,we put forward the necessity and foresight of integrating the “supercomputing mode”,i.e.,the combination of the computational simulation software and supercomputing platform,into the teaching process of chemistry classrooms,and explored the effective strategies to build a research-oriented classroom to promote the intelligent symbiosis of teaching and learning,and predicted the feasibility of expanding the supercomputing mode to other relevant courses.It is expected to be informative for strengthening the integration of education and research,education and production,and promoting innovative talents cultivation in science and engineering fields.
History of Chemistry and Chemical History Education

Construction and Practice of SMART Teaching Mode of Chemical History from the Perspective of Macro Science Education

LI Ling, SHU Ting-Ting
Chinese Journal of Chemical Education. 2025, 46 (18): 118-123. ;  doi: 10.13884/j.1003-3807hxjy.2024110099
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Based on the core value of the history of chemistry course in teacher education and addressing the pain points in the teaching of chemistry teacher training program at our university,the SMART teaching mode was constructed under the guidance of the holistic,developmental,and social concepts of the macro science education perspective.This mode innovates teaching methods and evaluation by integrating online resources,developing dynamic knowledge graphs,and introducing AI teaching assistants.Through teaching components including Student Sharing(S)-Presentation Scoring(M)-Perspective Evaluation(A)-Historical Reenactment(R)-Reflective Summary(T),it achieves interdisciplinary thinking training,guides critical reflection,internalizes scientific values,and empowers practice through technology,thereby enhancing pre-service teachers' subject literacy,critical thinking,and digital literacy.

CAO Huiqun's Translation of Modern Chemistry Concepts and Exploration of Scientific Education

LIU Wei, ZHONG Xue-Ming, DU Juan, YU Xin, CHEN Ai-Sheng
Chinese Journal of Chemical Education. 2025, 46 (18): 124-129. ;  doi: 10.13884/j.1003-3807hxjy.2025030033
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CAO Huiqun was a modern Chinese educator and chemist.In his early years,Mr.Cao went to the United Kingdom and studied modern science systematically,and returned to China in 1911, a historical turning point,contributed half of his life to the introduction of chemical concepts and the promotion of chemical education.From the three dimensions of philosophy in chemistry education,terminology translation,and promotion of science popularization and industry,combined with the examples ofCao Huiqun theeditor-in-chief for journals and periodicals,and support for the research and development of domestic chemical instruments,Cao Huiqun's proactive contributions in the historical tides of scientific education are reviewed.Cao Huiqun's image of“Grand Educator”on promoting the construction of the scientific education system in modern China,and devotion to the salvation of the nation through scientific education,is worthy of being learned and inherited by younger generations.
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