The most generalized disconnection used in retrosynthetic analysis of enones is the aldol condensation. But in some cases, enones can not be disconneted ideally by the aldol reaction. The alternative strategies such as aliphatic Friedel-Crafts acylation, Nazarov reaction, Baylis-Hillman reaction,intramolecular Stetter reaction and Diels-Alder reaction should be attempted according to the structures of target molecules.

Based on the strong theoretical nature, abstract content and rapid knowledge updating of biochemistry, this paper discussed the necessity of setting up biochemistry courses for chemistry education major in normal universities, as well as the reform of teaching content and teaching methods.

The "five-in-one" MBD (model-based discovery) teaching mode is developed for inquiry learning based on information processing theory and cognitive theory, which combined the basic theory of pedagogy and "four-in-one" model of informatics to further improve the proceduralness and scientificness of inquiry teaching. The comprehensive evaluation of "five-in-one" MBD teaching mode is an important indicator of the mode to develop subjective initiative of behavior subject in the actual teaching. However, due to a variety of factors, it is difficult to carry out quantitative assessment. Therefore, this article established a fuzzy evaluation model based on fuzzy mathematics and converted qualitative evaluation indexes to limited quantitative evaluation indexes to examine the timeliness and functionality of "five-in-one" MBD teaching mode in the actual teaching.

According to the long-term teaching experience of physical chemistry, this article analyzed the teaching materials and teaching contents of physical chemistry, and discussed how to teach physical chemistry well and carry out wide, fine and detailed education to cultivate basic and innovative minority talents with solid basic knowledge, comprehensive qualities, wide thinking and serious, meticulous and responsible spirit in ethnic minority area universities based on the teaching requirements and characteristics of the physical chemistry course.

This paper introduced a comprehensive experiment of synthesis and charaterization of ferrierite in two different hydrothermal systems. Based on the conventional hydrothermal crystallization methods, zeolites ferrierite (FER-type) were prepared by employing ethylenediamine and pyrrolidine as organic amine in two different hydrothermal systems, respectively. The resulting products were further characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), ²⁷Al MAS NMR, ²⁹Si MAS NMR analyses and nitrogen adsorption/desorption. From the view of experiment teaching, the entire experiment procedure was arranged reasonable, content-rich, easy to operate, fully reflected the "synthesis-characterization" thought of comprehensive scientific thinking mode, therefore, students would be familiar with the methods of the whole research process in inorganic chemistry and materials chemistry, and understand the basic process of scientific work.

According to the difficulties faced by experiment teaching of instrumental analysis and the advantages of virtual laboratory of instrumental analysis in current universities, this paper proposed a multi-level and student-centered construction mode of virtual laboratory of instrumental analysis, and introduced application patterns in teaching to make full use of virtual laboratory to promote experiment teaching of instrumental analysis.

This paper designed a teaching experiment program to study oxidability of ozone by using self-made distributary ozone generator and choosing organophosphorus pesticide glyphosate as an object. The experiment program included the determination of the amount of ozone, the determination of orthophosphate ions degraded from glyphosate, the conversion of glyphosate to orthophosphate ions, and the conversion curve of glyphosate degradation with time. Through this experiment, students could deeply understand and master the oxidation properties of ozone and its research methods. The research-oriented experiment was innovative and practical, and has been successfully used in teaching experiment of environmental chemistry for undergraduate.

This paper used a homemade safe transfer instrument combining tubes opening into atmosphere and liquid bromine respectively, bottle stopper and absorption sphere filled with acticarbon to transfer liquid bromine safely. This method could avoid the loss of bromine by volatilization and ensure the safety of operators.

Investigation showed that five factors including attitude to teaching practice, teachers' guidance, class hours of training, simulation of actual classroom and objectivity of teaching practice evaluation influenced teaching practice abilities of pre-service chemistry teachers. According to the analysis of these factors, this paper proposed some suggestions such as establishing a complete and objective evaluation system, changing pre-service teachers' perception to practice, strengthening teaching simulation training and the execution of teaching practice, etc., to improve pre-service teachers' teaching practice abilities.

Construction of curriculum system to specialty group is the key to the formulation of professional talent cultivation plan in high vocational education. According to the work requirements of plastic additives production and typical work tasks, fine chemicals processing major in Changzhou institute of light industry and technology constructed the curriculum system including the public courses, engineering curriculum group, plastic additives synthesis curriculum group and selected curriculum in the specialty groups, combining other specialties, promoted the whole curriculum construction of fine chemicals processing major by emphasizing the development of core curriculum of the plastic additives synthetic curriculum group.

This paper discussed how to set contexts to improve teaching of physical chemistry for undergraduate students majoring in non chemistry from two aspects with detailed examples. Firstly, in order to stimulate students' interests in each chapter of physical chemistry, this paper presented how to set contexts according to the characteristics of majors to make students feel the importance of each chapter to the follow-up study. Secondly, this paper discussed how to help students study detailed knowledge in physical chemistry by the anchored instruction method with contexts setting.

According to students' inactive study attitude and weak pertinence of chemistry teaching in fire education, this paper summarized chemical knowledge and chemical analysis methods in the fire site identification, chemical separation and analysis methods of fire evidence for fire investigation to stimulate students' interests in learning and using chemistry, and provided practical teaching cases for other majors

Based on brief introduction of significance and status of chemical education in military academy, this paper expounded some concrete measures for strengthening the chemical education in Military Transportation Institute, introduced some ideas on strengthening the chemical education in military academy.

Based on the analysis of the status and difficulties of experiments for teaching method and advantages of chemical simulation experiment platform, this paper proposed to apply the chemical simulation experiment platform to experiments for teaching methods of high school chemistry. Results showed that chemical simulation experiment platform had practical value in experiments for high school chemistry teaching method training in normal university.

Under the guidance of constructivism learning theory and on the basis of developing a network learning platform, this paper presented a reform strategy of network-based classroom teaching mode with example of analytical chemistry course. The core of reform strategy was three transformations including role transition between teachers and students, conversion of textbook and teaching time-space conversion through the effective arrangement of classroom teaching contents, the assistance of network learning platform and the reform of assessment method for student achievements to improve the effectiveness of classroom teaching and the quality of talent training.

The investigation showed that the scientific inquiry ability of students major in preschool education was very low, the students were not familiar with the complete process of scientific inquiry, rarely experienced in all aspects of the process of scientific inquiry. So,normal colleges should pay attention to science courses, writes science curriculum standards of scientific inquiry, implement the curriculum standards strictly, select appropriate inquiry content, use inquiry teaching method.

This article presented insight and understanding of several important issues in organic chemistry such as the 1,2 and 1,4 addition of the conjugated olefin, the intramolecular dehydration and intermolecular dehydration of ethanol, the mechanism of aldol condensation, the choice of catalyst in ester condensation, and the assignment of R or S configuration of a stereocenter, etc.The discussions of the above concepts have been carried out with students in the course, and good teaching effect has been received.

With thermodynamics, it is well explained that water seal on mercury surface is very effective for preventing the volatilization of mercury. Furthermore, if an immiscible multi-component system is steady placed, the volatilization of the phase with a greater density will be blocked by the top phase with a minimum density. A misconception exists in some physical chemistry textbooks, courseware, and many teachers' teaching process is stated. This is important for correct understanding of the phase equilibrium of immiscible dual liquid system, a type of common natural phenomena, effective use and control of such system.

The emergence and development of anesthetic have made an indelible contribution to relieving human pain. China was the earliest country using the narcotic drug. There was "poison" in Warring States Period, "MaFeiSan" made by Hua Tuo in later Eastern Han Dynasty, "Sleeping Saint San" in Song Dynasty, "Knockout Drops" in Ming Dynasty. In western countries, the earliest used modern anesthetic was "laughing gas", ether and other narcotic drugs appeared subsequently. With the rapid development of modern chemistry, the widely use of anesthetics like xenon, propofol and sugammadex has greatly contributed to relieve human pain.