Metal nanoclusters (MNCs) is composed by the metal core of hundreds atoms which is coated by a layer of complex. The structure of MNCs can be tuned at the atomic level. The small size, unique electron energy levels and large specific surface area enable MNCs to be applied widely in various fields. The definition, structure, performance, synthesis and application of MNCs in catalysis, biosensing, bioimaging, and oncotherapy are presented mainly based on the reports in reference about research focuses on CuNCs,AgNCs and AuNCs.

Organophosphine catalysis is an environmentally friendly organic synthesis method with mild reaction conditions, which has been widely used in the field of organic synthesis. Among them, cyclization and cycloaddition reactions catalyzed by nucleophilic organophosphines have gradually developed into one of the important tools for the construction of carbocyclic and heterocyclic compounds and natural products. This paper introduces the methodology of organophosphine-catalyzed cyclization and cycloaddition reactions, and the application research progress of organophosphine-catalyzed annulation reactions in the total synthesis of natural products in recent years.

The general education course is an important part of the teaching content of colleges and universities, and has a profound effect on improving the quality of undergraduate students. The teaching content of the general education course, chemistry and health, involves the subjects such as chemistry, life, pharmacology, medicine and environment, which can broaden the students' knowledge, promote multidisciplinary cross, and achieve the goal of improving scientific literacy for students. Based on the teaching practice of this course in a comprehensive university, the construction basis, course objective and teaching content design, teaching method, and the introduction of the thinking policy are discussed in the paper. It will provide the reference for strengthening the general education course construction in comprehensive universities.

As the core course of chemical engineering and technology specialty, principles of chemical engineering bridge the gap from theory to engineering and from foundation to specialty. It plays an important role in cultivating new engineering talents with engineering viewpoint, practical skills and innovation ability. How to integrate the professional theoretical knowledge and practical ability, so that the two complement each other, is the key to teaching. Through questionnaire surveys of students and teaching practice, this paper proposes some feasible teaching reform measures in order to achieve all-round training of students.

It is of great significance to carry out ideological and political education with rare earth elements as the carrier in the analytical chemistry class for solving the problem of “stuck neck” in the field of rare earth high-tech development in China. Here, the construction ideas of integrating the rare earth elements into the analytical chemistry course are discussed. As well, how to play the carrier role of rare earth elements and realize the all-round and whole process objectives of ideological and political construction are demonstrated, and specific practical cases are given.

Ideological and political education can be integrated into the teaching of the specialized course “fine chemical chemistry”. Plenty of ideological and political education elements can be exploited through a close connection with the knowledge points of this course and the teacher's role of cultivating students' virtue and morality can be fully played. With ideological and political education integrated in the course, students' concepts of green development and quality development can be cultivated. They may increase their awareness of serving the people, promote innovative spirit and professional dedication, develop their scientific way of thinking and research methods and form correct values and a correct outlook on life. This paper explored the implementation strategy of ideological and political education in “fine chemical chemistry” to improve the comprehensive quality of students and therefore, transport high-quality fine chemical talents for the society.

Under the background of the national green transformation and achievement of carbon peak and carbon neutralization, this paper introduced the teaching reform of electrochemistry in physical chemistry course. Proton exchange membrane water electrolyzer technology was introduced to illustrate the electrolysis cell, decomposition voltage, polarization curve, overpotential and electrode reaction kinetics. Electrochemical CO₂ reduction and N₂ reduction were used as case-study materials for after-class discussion in structured group. The task driven teaching method was combined to consolidate the basic knowledge, accompanied with fully improving of the autonomous learning ability, practical application ability and innovation ability. Meanwhile, ideological value guidance ran through the whole education teaching process to cultivate students' political literacy and social responsibility.

Under the background of “top talent training program” 2.0, the curriculum system of organic chemistry laboratory in Peking University has been established. The core target is to comprehensive cultivate students' scientific literacy and ability. The training of scientific research method is the main line of teaching. The basic operation, synthesis technology, open experiment, computational experiment, literature research, scientific writing and other teaching modules are fully integrated. Through the teaching design based on understanding and the blended teaching mode, the hierarchical teaching is carried out to enhance the ability of students' autonomous learning and cooperative learning and promote the growth of students.

The evaluation of the achievement of courses is the basis of the evaluation of the achievement of professional talent training goals and graduation requirements, and is one of the important examination contents in the certification of teachers' majors. Organic chemistry experiment is a compulsory practical course for chemistry major. In order to reasonably evaluate the teaching quality and teaching effect of this course, took the organic chemistry experiment course of chemistry major of Neijiang Normal University as an example, introduced the basic information of the course, the course goals and its support for graduation requirements index points. From formative evaluation and summative evaluation, direct evaluation and indirect evaluation, comprehensive evaluation, etc., the evaluation process and the application of evaluation results were introduced in detail. The research results provide references for the teaching reform and teaching quality evaluation of related courses.

In this paper, we designed a series of microfluidic chip systems to demonstrate classical experiments such as acid-base neutralization, coordination, redox reaction, because the microfluidic chips pose the advantages of high efficiency, low consumption and microscale analysis. Through the effects of laminar flow, interface reaction and radial diffusion in microscale, the demonstration experiment induced by interface diffusion was established. And the whole process was shown in the way of slow-motion band. It can make the reaction easy to operate, and demonstrate the intersection of multi-disciplinary knowledge. During the teaching process among senior high school students, undergraduates and junior college students with different knowledge background, we can carry out various training plans for target students at different levels under ordinary experimental conditions. The experimental operation is easy for manipulation, the amount of reagent is less (several milliliters), the time is short (a few minutes), and the space is small. It also exhibits green and safety features, so is suitable to be widely carried out in the experimental teaching in colleges and middle schools.

Instructional design competence is an important part of the cultivation of normal students' instructional competence. Using the combination of qualitative and quantitative methods, this study constructs the composition model and progression model of normal students' chemical instructional design competence from three dimensions of instructional design knowledge, instructional design skills and instructional design attitude and consciousness. Two evaluation tools, teaching case analysis and questionnaire, are developed to make an empirical study on the chemistry instructional design competence of normal students, and explore the development and advancement of chemistry instructional design competence of normal students in the course of middle school chemistry instructional design and practice. The results show that the knowledge of instructional design of normal students has developed from single to diversified, the skills of instructional design have advanced from no angle to multiple angles, and the attitude and consciousness of instructional design have developed from negative and self-doubt to positive and self-confident.

The application of artificial intelligence (AI) in active molecule discovery and drug screening has become increasingly in-depth, innovating the traditional way of discovering natural drugs, reconstructing the pattern of drug discovery and design. This requires talents to be proficient in the basic knowledge of natural medicinal chemistry, have the ability to analyze problems across multiple disciplines, cultivate and establish logical thinking that keeps pace with the times. To meet the development requirements of the AI era, natural medicinal chemistry teaching needs to build a teaching system for AI to participate in natural drug discovery, provide intuitive teaching for AI to participate in natural drug discovery, select excellent online teaching resources to guide students to learn independently, and cultivate students' thinking ability in AI's participation in natural drug discovery.

In terms of the strong theoretical and abstract characteristics of inorganic non-metallic material chemistry course, this paper discusses how to introduce cutting-edge scientific research results into teaching. Application of point defect engineering in hydrogen energy technology is taken as an example. Through case studies, we intend to deepen students' understanding of theoretical knowledge, stimulate students' interests in learning, and cultivate students' scientific research ability.

In view of the problems existing in the specialty of chemical engineering and process characterized by salt manufacturing and chemical industry in Tianjin University of Science and Technology, we reformed the curriculum system, teaching practice and teacher team based on the demands of talent training for the transformation and upgrading of traditional salt chemical industry and the construction of new emerging engineering. A “chemical engineering+” curriculum system with multi-disciplinary integration has been established. A multi-dimensional practical teaching mode of virtual-real experiment, everyone doing design, and the combination of professional courses, scientific research projects and graduation thesis has been constructed. And a qualified teacher team with theory and engineering capabilities who are suitable for the emerging engineering education has been established. After nearly four years of exploration and practice, the specialty has made a series of achievements in first-class curriculum construction, teaching research and reform, and innovative practice of teachers and students. It greatly improved the students' ability to innovate and solve complex engineering problems, and cultivated a number of high-quality students with the engineering and technical in salt manufacturing and chemical industry.

The intermolecular hydrogen bonding interactions between ALAD and water molecules were revealed with the help of VMD software for the understanding of molecular structure of polypeptides during classroom teaching of application of computer in chemistry. It can show us the 3D animation of hydrogen bonds, and decipher the hydrogen bond interactions between polypeptides and water molecules in qualitative and quantitative perspectives. Thus, teachers' teaching methods could be enriched, and students' core ability of chemistry such as macro identification and micro analysis, evidence-based reasoning and model cognition could be improved.

Practical teaching plays an important role in the course of cheminformatics, which mainly carries out in the computer room. Recently, the comprehensive practical teaching of cheminformatics, as an important supplement to the practical class in the computer room, is of significance to improve the teaching effect of cheminformatics and the undergraduate students' training. This paper expounds on the main points of the comprehensive practice teaching of cheminformatics, and introduces the details of the teaching through a teaching case. Besides, the feedback of comprehensive practice teaching of cheminformatics has been obtained through the questionnaire to evaluate the effects.

The study described the college students' note-taking behavior in chemistry class from five aspects: note-taking content, note-taking location, note-taking format, note-taking detail level and note-taking coding level. The study analyzed the college students' note-taking behavior characteristics in chemistry class, and compared note-taking behavior with different academic levels, and put forward teaching suggestions for improving college students' note-taking behavior.

Nucleophilic 1,2-rearrangements are one class of important organic reactions. Leaving of the leaving groups and shift of the shift groups can be either stepwise or concerted. However, the rearrangements always occur with retention of the configuration at the migrating carbon of the shift groups. This article introduces using hyperconjugation and stereoelectronic effect to explain the phenomenon and to grasp the general rule, hoping to provide help for teachers' teaching and students' understanding in teaching and learning organic chemistry.

In this paper, we summarized the concepts and units of magnetic field, magnetic induction field, magnetic moment, magnetization, magnetic susceptibility in the research of molecular magnetism. The conversion of these physical quantities between the SI and EMU unit system is clearly demonstrated. Moreover, the application of fundamental equation in molecular magnetism, Van Vleck equation as well as the Brillouin function to calculate the mole magnetization and mole magnetic susceptibility is also discussed.

The calculating of the degree of polymerization in the linear condensation polymerization, and the teaching experience of the corresponding section for undergraduate students are discussed. It is found that during the teaching, the traditional calculation equation is easy to cause students' misunderstanding and confusion. In this paper, a new parameter is defined and the corresponding calculation equations are developed to make the new equation clear and simple. This new parameter is clearly defined, easy for students to understand and master, and good teaching results have been achieved in the teaching practice.